Find a veterinarian who can help your dog - and you.

PROIN® – the safe and effective way to control canine incontinence due to sphincter hypotonus

Every year, thousands of dogs are relinquisthed to shelters, and the number-one reason (18.5%) is for soiling in the house.1 Yes, it's frustrating and maddening when your housebroken dog suddenly seems unable to hold it. But chances are she's not doing it on purpose.

Leaking urine is a medical issue – one that can be easily addressed. Prescribed by your veterinarian, PROIN® may help put your dog back in control. Proven safe and effective, this affordable FDA-approved medication has been shown to successfully manage canine urinary incontinence2 without impacting your dog's ability to live a normal life.

Designed with you and your dog in mind

Giving your dog medication can sometimes be a real chore, requiring tons of patience and cheese or peanut butter. But this isn’t the case with PROIN. Available in three strengths and scored tablets for flexible dosing, PROIN is chewable and liver flavored. That means you don’t need to force feed the pill or wrap it in cheese, and your dog will think she’s getting a tasty treat.

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Using Proin

Follow the dosing instructions prescribed by your veterinarian. Before using PROIN, refer to this important safety information.

Take your dog for frequent walks, especially first thing in the morning or after she wakes from a nap.

Always keep the bottle out of the reach of children and your dog. Consult a physician in case of accidental ingestion by humans.

Continuously monitor your dog’s health and notify your veterinarian of any changes in her condition.

Ensure your dog always has ample fresh drinking water available.

Enjoy having a dog again by ensuring she stays happy and healthy – and a beloved member of your family.

Get the pill that can
end the spills

Talk to your veterinarian about PROIN - a convenient, chewable tablet that can put your dog back in control.

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about the wet.

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Find a veterinarian who can help your dog - and you.

IMPORTANT SAFETY INFORMATION: For oral use in dogs only. Not for human use. Keep out of reach of children. If accidentally ingested by humans, contact a physician immediately. The most commonly reported side effects were vomiting, loss of appetite, diarrhea, excessive salivation, agitation, tiredness, vocalization, confusion, increased water consumption, weight loss, weakness, fever, panting, and reversible changes in skin color (flushing or bright pink). Abnormal gait, seizures or tremors, as well as liver enzyme elevations, kidney failure, blood in urine and urine retention have been reported. In some cases death, including euthanasia has been reported. Sudden death was sometimes preceded by vocalization or collapse. Instances of dogs chewing through closed vials of PROIN and eating the vial contents have been reported, in some cases resulting in overdose. Keep the product in a secured storage area out of the reach of pets in order to prevent accidental ingestion or overdose, as dogs may willingly consume more than the recommended dosage of PROIN Chewable tablets. Contact your veterinarian immediately if the dog ingests more tablets than prescribed or if other pets ingest PROIN Chewable tablets. PROIN may cause elevated blood pressure and should be used with caution in dogs with pre-existing heart disease, high blood pressure, liver disease, kidney insufficiency, diabetes, glaucoma, and other conditions associated with high blood pressure. The safe use of PROIN in dogs used for breeding purposes, during pregnancy or in lactating bitches, has not been evaluated. Contact your veterinarian if you notice restlessness or irritability, loss of appetite, the incontinence persists or worsens or any other unusual signs. See prescribing information for complete details regarding adverse events, warning and precautions or visit
Refer to the full prescribing information for complete details. NADA#141-324 Approved by FDA
PROIN is a registered trademark of Pegasus Laboratories, Inc.